Player Draft
| Name | State | School | Class | Pos. | Year | Round | Team |
| Javen Coleman | TX | Home School | 2020 | LHP | 2023 | 16 | Dodgers |
| Dennis Colleran | MA | North Attleboro | 2021 | RHP | 2024 | 7 | Royals |
| TJ Collett | IN | Terre Haute North Vigo | 2016 | 1B | 2016 | 40 | Twins |
| Keshun Collier | MS | Mendenhall | 2020 | OF | 2022 | 20 | Cubs |
| Cam Collier | GA | Mount Paran | 2022 | 3B | 2022 | 1 | Reds |
| Isaac Collins | MN | Maple Grove | 2016 | 2B | 2019 | 9 | Rockies |
| Corey Collins | GA | North Gwinnett | 2020 | C | 2024 | 6 | Mets |
| Gavin Collyer | GA | Mountain View | 2019 | RHP | 2019 | 12 | Texas Rangers |
| Dalton Combs | IN | Adams Central | 2013 | OF | 2017 | 35 | Giants |
| Aaron Combs | FL | IMG Academy | 2020 | RHP | 2024 | 8 | White Sox |
| Chris Comito | IA | Norwalk | 2015 | RHP | 2015 | 15 | White Sox |
| Charlie Condon | GA | The Walker School | 2021 | 1B | 2024 | 1 | Rockies |
| Griffin Conine | FL | Pine Crest | 2015 | OF | 2015 | 31 | Marlins |
| Cal Conley | OH | West Clermont | 2018 | SS | 2021 | 4 | Atlanta Braves |
| Shane Conlon | IL | Naperville Central | 2010 | LHP | 2013 | 21 | Royals |
| Jack Conlon | TX | Clements | 2017 | RHP | 2017 | 4th | Baltimore |
| Cole Conn | IL | St. Charles East | 2020 | C | 2023 | 12 | Athletics |
| Justin Connell | FL | American Heritage | 2017 | SS | 2017 | 11 | Nationals |
| Charlie Connolly | PA | Radnor | 2017 | RHP | 2021 | 20 | Dodgers |
| Shane Connolly | NC | Pine Lake Preparatory | 2017 | RHP | 2021 | 10 | Royals |
| Caden Connor | CA | Orange Lutheran | 2019 | OF | 2023 | 19 | White Sox |
| Drew Conover | NJ | Voorhees | 2020 | RHP | 2022 | 20 | Tigers |
| Nicholas Conte | RI | North Providence | 2020 | RHP | 2024 | 8 | Royals |
| Nick Conti | FL | Dr Phillips | 2015 | 2B | 2015 | 40 | Mets |
| Gavin Conticello | FL | Stoneman Douglas | 2021 | SS | 2021 | 8 | Arizona Diamondbacks |
| Austin Conway | IN | Delta | 2013 | RHP | 2018 | 31 | White Sox |
| Sean Cook | MD | Walt Whitman | 2016 | RHP | 2016 | 40 | Nationals |
| Casey Cook | VA | Freedom (South Riding) | 2021 | OF | 2024 | 3 | Rangers |
| Alex Cook | GA | Apalachee | 2019 | RHP | 2022 | 12 | Rays |
| Sam Coonrod | IL | Carrollton | 2011 | RHP | 2014 | 5 | Giants |
| Shane Cooper | MO | Timberland | 2013 | 2B | 2017 | 37 | Tigers |
| Tanner Cooper | NY | Canandaigua Academy | 2017 | RHP | 2019 | 35th | Cincinatti Reds |
| Riley Cooper | CA | Clovis North | 2020 | LHP | 2023 | 13 | Orioles |
| Everett Cooper | NC | Pro5 Academy | 2022 | SS | 2022 | 16 | Nationals |
| Patrick Copen | WV | Parkersburg Catholic | 2020 | RHP | 2023 | 7 | Dodgers |
| Billy Corcoran | PA | Malvern Prep | 2018 | RHP | 2018 | 36 | Rangers |
| Matthew Corlew | FL | North Broward Prep | 2019 | OF | 2019 | 23rd | Los Angeles Angels |
| Riley Cornelio | CO | Pine Creek | 2019 | RHP | 2022 | 7 | Nationals |
| Chris Cornelius | MO | Vianney | 2016 | SS | 2019 | 16 | Phillies |
| Octavio Corona | CA | Otay Ranch | 2019 | RHP | 2019 | 39th | Blue Jays |
| Carlos Cortes | FL | Lake Howell | 2016 | OF | 2016 | 20 | Mets |
| Chris Cortez | NV | Silverado | 2021 | RHP | 2024 | 2 | Angels |
| Harold Cortijo | MD | Riverdale Baptist | 2017 | RHP | 2017 | 14 | Yankees |
| Andrew Cossetti | PA | La Salle | 2018 | C | 2022 | 11 | Twins |
| Mike Costanzo | IL | St. Rita | 2014 | LHP | 2018 | 31 | Rays |
| Jack Costello | CA | Chaminade Prep | 2020 | 3B | 2024 | 10 | Padres |
| Marty Costes | MD | Archbishop Curley | 2015 | OF | 2017 | 25 | Astros |
| Magdiel Cotto | SC | Nation Ford | 2020 | LHP | 2023 | 11 | Pirates |
| Quin Cotton | CO | Regis Jesuit | 2016 | OF | 2016 | 38 | Rockies |
| Paul Coumoulos | FL | College of Central Florida | 2017 | OF | 2017 | 40 | Phillies |
| Isaiah Coupet | IL | Homewood-Flossmoor | 2020 | LHP | 2023 | 4 | Rockies |
| Jake Cousins | IL | Wheaton | 2013 | RHP | 2017 | 20 | Nationals |
| Benjamin Cowles | NY | Newark | 2018 | SS | 2021 | 10 | New York Yankees |
| Jonah Cox | CO | Broomfield | 2020 | OF | 2023 | 6 | Athletics |
| Jackson Cox | WA | Toutle Lake | 2022 | RHP | 2022 | 2 | Rockies |
| Brenner Cox | TX | Prosper Rock Hill | 2022 | OF | 2022 | 4 | Nationals |
| Jacob Cozart | NC | Wesleyan Christian | 2021 | C | 2024 | 2 | Guardians |
| Dylan Craig | IL | Murphysboro | 2011 | LHP | 2014 | 12 | Rockies |
| Trendon Craig | MD | Riverdale Baptist | 2019 | OF | 2021 | 20 | Baltimore Orioles |
| Luke Craig | NC | Southern Lee | 2020 | LHP | 2024 | 7 | Diamondbacks |
| Adam Crampton | CA | Oakland Technical | 2019 | SS | 2022 | 9 | Orioles |
| Hunter Cranton | CA | JSerra Catholic | 2019 | RHP | 2024 | 3 | Mariners |
| Robert Cranz | TX | Keller | 2021 | SS | 2024 | 7 | Nationals |
| Jacob Cravey | AL | Andalusia | 2020 | RHP | 2023 | 6 | Orioles |
| Reggie Crawford | PA | North Schuylkill | 2019 | LHP | 2022 | 1 | Giants |
| Justin Crawford | NV | Bishop Gorman | 2022 | OF | 2022 | 1 | Phillies |
| Ashton Creal | IL | Metea Valley | 2017 | OF | 2019 | 21 | Reds |
| Riley Crean | IN | Bloomington North | 2017 | RHP | 2017 | 35 | White Sox |
| Wyatt Crenshaw | AZ | N/A | 2018 | OF | 2023 | 19 | Diamondbacks |
| Dylan Crews | FL | Lake Mary | 2020 | OF | 2023 | 1 | Nationals |
| Kyle Crigger | MS | Corinth | 2017 | SS | 2022 | 7 | Marlins |
| Demetrio Crisantes | AZ | Nogales | 2022 | SS | 2022 | 7 | Diamondbacks |
| Larry Crisler | IN | Bishop Noll | 2014 | OF | 2014 | 36 | Braves |
| Jeff Criswell | MI | Portage Central | 2017 | RHP | 2017 | 35 | Tigers |
| Garrett Crochet | MS | Ocean Springs | 2017 | LHP | 2017 | 34 | Brewers |
| David Cronin | IL | Sandburg | 2013 | 2B | 2017 | 20 | White Sox |
| Jimmy Crooks | TX | Trinity | 2019 | C | 2022 | 4 | Cardinals |
| Wyatt Cross | CO | Legacy | 2015 | C | 2015 | 33 | Rockies |
| Matthew Cross | NY | Starpoint | 2016 | C | 2018 | 19th | Oakland Athletics |
| Gavin Cross | TN | Tennessee | 2019 | OF | 2022 | 1 | Royals |
| Logan Crouse | FL | Bloomingdale | 2015 | RHP | 2015 | 30 | Dodgers |
| Coleman Crow | GA | Pike County | 2019 | RHP | 2019 | 28 | Los Angeles Angels |
| Pete Crow-Armstrong | CA | Harvard-Westlake | 2020 | OF | 2020 | 1 | NY Mets |
| Jack Crowder | IL | Plainfield East | 2020 | RHP | 2024 | 9 | Orioles |
| Wyatt Crowell | GA | West Forsyth | 2020 | LHP | 2023 | 4 | Dodgers |
| Ryan Crowley | IL | Morton | 2009 | LHP | 2011 | 19 | Angels |
| Ronny Cruz | FL | Miami Christian | 2024 | SS | 2024 | 3 | Cubs |
| Kaelan Culpepper | TN | St. Benedict | 2021 | SS | 2024 | 1 | Twins |
| Christian Culpepper | CA | Rancho Cucamonga | 2019 | RHP | 2022 | 13 | Twins |
| Brad Cumbest | MS | East Central | 2018 | OF | 2022 | 9 | Rockies |
| Ty Cummings | NC | Corinth Holders | 2020 | RHP | 2023 | 7 | Mariners |
| Carter Cunningham | VA | Battlefield | 2019 | OF | 2024 | 10 | Blue Jays |
| Bryce Cunningham | AL | Headland | 2021 | RHP | 2024 | 2 | Yankees |
| Jake Cunningham | NC | Ardrey Kell | 2021 | OF | 2023 | 5 | Orioles |
| Luis Curbelo | FL | Cocoa | 2016 | SS | 2016 | 6 | White Sox |
| Michael Curialle | CA | JSerra | 2019 | SS | 2022 | 12 | Cardinals |
| Brian Curley | VA | Trinity Episcopal | 2022 | RHP | 2024 | 16 | Pirates |
| Aidan Curry | NY | Fordham Prep | 2020 | RHP | 2020 | Undrafted Free | Texas Rangers |
| Khristian Curtis | TX | Port Neches-Groves | 2020 | RHP | 2023 | 12 | Pirates |
| Ryan Cusick | CT | Avon Old Farms | 2018 | RHP | 2021 | 1 | Atlanta Braves |