Player Draft
| Name | State | School | Class | Pos. | Year | Round | Team |
| Nick Decker | NJ | Seneca | 2018 | OF | 2018 | 2 | Boston Red Sox |
| Brandon Decker | MI | North Farmington | 2020 | RHP | 2024 | 19 | Yankees |
| Cameron Decker | IN | Evansville North | 2022 | 3B | 2022 | 18 | Dodgers |
| Craig Dedelow | IN | Munster | 2013 | OF | 2017 | 9 | White Sox |
| Nick Deeg | MI | Lake Orion | 2013 | LHP | 2016 | 30 | Giants |
| Bailey Dees | NC | Hough | 2017 | RHP | 2021 | 18 | New York Yankees |
| Jaycob Deese | TX | North Shore | 2018 | RHP | 2022 | 17 | Pirates |
| Dean Deetz | MO | Nixa | 2012 | RHP | 2014 | 11 | Astros |
| Ryan Degges | TN | Christian Academy of Knoxville | 2021 | RHP | 2024 | 17 | Phillies |
| Josh Degraaf | IL | Morris | 2011 | RHP | 2015 | 31 | Blue Jays |
| Jack DeGroat | VA | Loudoun Valley | 2015 | RHP | 2018 | 11 | Indians |
| Kyle DeGroat | NY | Wallkill | 2024 | RHP | 2024 | 14 | Royals |
| Paul DeJong | IL | Antioch | 2011 | 3B | 2015 | 4 | Cardinals |
| Jacob DeLabio | WI | Tremper | 2016 | RHP | 2021 | Free Agent | Houston Astros |
| Chase DeLauter | WV | Hedgesville | 2019 | OF | 2022 | 1 | Guardians |
| Jake DeLeo | CT | Avon Old Farms | 2020 | OF | 2023 | 6 | Marlins |
| Joseph Delossantos | VA | Granville Central | 2019 | OF | 2024 | 10 | Yankees |
| Dylan DeLucia | FL | New Smyrna Beach | 2019 | RHP | 2022 | 6 | Guardians |
| Carson DeMartini | VA | Ocean Lakes | 2021 | SS | 2024 | 4 | Phillies |
| Mason Denaburg | FL | Merritt Island | 2018 | RHP | 2018 | 1st | Washington Nationals |
| Matt Dennis | IL | Rolling Meadows | 2013 | RHP | 2016 | 14 | Rockies |
| Bryce Denton | TN | Ravenwood | 2015 | 3B | 2015 | 2 | Cardinals |
| Cade Denton | TX | Dallas Christian | 2020 | RHP | 2023 | 6 | Rockies |
| Jake DePew | IL | Granite City | 2010 | C | 2010 | 9 | Rays |
| Domenic DeRenzo | PA | Pittsburgh Central Catholic | 2015 | C | 2015 | 40 | Cubs |
| Nick Derr | FL | Sarasota | 2016 | SS | 2016 | 33 | Reds |
| Reid Detmers | IL | Glenwood | 2017 | LHP | 2017 | 32 | Braves |
| Nathan Dettmer | TX | Johnson | 2020 | RHP | 2023 | 5 | Athletics |
| Ricky DeVito | NY | St Joseph by the Sea | 2016 | RHP | 2019 | 8 | Braves |
| Nolan DeVos | NC | Hickory Ridge | 2019 | RHP | 2022 | 5 | Astros |
| Zach Dezenzo | OH | Marlington | 2018 | SS | 2022 | 12 | Astros |
| Derek Diamond | CA | Ramona | 2019 | RHP | 2022 | 5 | Pirates |
| Khadim Diaw | CA | Notre Dame | 2021 | C | 2025 | 3 | Twins |
| Davis Diaz | CA | Acalanes | 2021 | SS | 2024 | 8 | Athletics |
| Jatnk Diaz | PA | Hazleton Area High School | 2023 | 1B | 2023 | 8 | Tigers |
| Randal Diaz | PR | Leadership Christian Academy | 2021 | 2B | 2024 | 5 | Nationals |
| Jared DiCesare | VA | Chantilly | 2016 | RHP | 2019 | 17th | Blue Jays |
| Sonny DiChiara | AL | Hoover | 2018 | 1B | 2022 | 5 | Angels |
| Korbyn Dickerson | KY | Trinity | 2022 | OF | 2022 | 20 | Twins |
| Dustin Dickerson | MS | West Jones | 2019 | 3B | 2023 | 8 | Royals |
| Blake Dickerson | VA | Ocean Lakes | 2023 | LHP | 2023 | 12 | Padres |
| Luke Dickerson | NJ | Morris Knolls | 2024 | SS | 2024 | 2 | Nationals |
| Jared Dickey | TN | Friendship Christian | 2020 | OF | 2023 | 11 | Royals |
| Tristan Dietrich | PA | Owen J. Roberts | 2023 | LHP | 2023 | 18 | Marlins |
| Matthias Dietz | IL | Sandburg | 2014 | RHP | 2016 | 2 | Orioles |
| Thomas Dillard | MS | Oxford | 2016 | OF | 2019 | 5 | Brewers |
| Mark DiLuia | IL | Marian Catholic | 2017 | RHP | 2017 | 38 | Rangers |
| Max Dineen | NJ | Pennsville | 2018 | OF | 2018 | 35 | Cincinatti Reds |
| Marco Dinges | FL | East Lake | 2021 | C | 2024 | 4 | Brewers |
| Owen Diodati | ON | A.N. Myer | 2019 | OF | 2019 | 29 | Toronto Blue Jays |
| Jordan Dissin | PA | Malvern Prep | 2020 | C | 2022 | 12 | Phillies |
| JD Dix | WI | Whitefish Bay | 2024 | SS | 2024 | CB-A | Diamondbacks |
| Jasiah Dixon | CA | Orange Lutheran | 2019 | OF | 2019 | 23 | Pirates |
| Joey Dixon | UT | Bingham | 2020 | RHP | 2023 | 7 | Astros |
| Brad Dobzanski | NJ | Delsea | 2017 | RHP | 2017 | 39 | San Francisco Giants |
| Dylan Dodd | IL | Danville | 2016 | LHP | 2021 | 3 | Atlanta Braves |
| Griffin Doersching | WI | Greendale | 2017 | 1B | 2022 | 8 | Padres |
| Marquise Doherty | MO | Winnetonka | 2015 | OF | 2015 | 15 | Royals |
| Steve Doherty | CA | Vancouver College, Canada | 1993 | SS | 1997 | 45 | Arizona Diamondbacks |
| Nate Dohm | IN | Zionsville | 2021 | RHP | 2024 | 3 | Mets |
| Chase Dollander | GA | Greenbrier | 2020 | RHP | 2023 | 1 | Rockies |
| Trey Dombroski | NJ | Wall | 2019 | LHP | 2022 | 4 | Astros |
| Michael Dominguez | FL | Jefferson | 2019 | RHP | 2019 | 15th | Toronto Blue Jays |
| Anthony Donofrio | NY | St. Anthony's | 2018 | OF | 2024 | 10 | Mariners |
| Charlie Donovan | IL | Westmont | 2015 | SS | 2015 | 30 | Brewers |
| Joe Donovan | IL | Westmont | 2017 | C | 2017 | 33 | Cubs |
| Ethan Dorchies | IL | Cary-Grove | 2024 | RHP | 2024 | 10 | Brewers |
| Ryan Dorow | MI | South Haven High School (LC Mohr) | 2013 | SS | 2017 | 30 | Rangers |
| Nathan Dorris | IL | Marion | 2009 | LHP | 2012 | 17 | Cubs |
| Carson Dorsey | FL | J.R. Arnold | 2021 | LHP | 2024 | 7 | Orioles |
| Terence Doston | FL | Hillsborough | 2019 | OF | 2019 | 22nd | Milwaukee Brewers |
| Destin Dotson | LA | Scotlandville Magnet | 2018 | LHP | 2018 | 12th | Rangers |
| Jack Dougherty | TN | Collierville | 2020 | RHP | 2023 | 9 | Twins |
| Cade Doughty | LA | Denham Springs | 2019 | 2B | 2022 | 2C | Blue Jays |
| Braylon Doughty | CA | Chaparral | 2024 | RHP | 2024 | CB-A | Guardians |
| Drew Dowd | CA | Serra | 2020 | LHP | 2023 | 8 | Rays |
| Brandon Downer | CA | Santiago | 2021 | RHP | 2024 | 13 | Orioles |
| Jeter Downs | FL | Pace | 2017 | SS | 2017 | 1 | Reds |
| Brenton Doyle | VA | Kettle Run | 2016 | OF | 2019 | 4th | Rockies |
| Tommy Doyle | VA | Flint Hill | 2014 | RHP | 2017 | 2 | Rockies |
| Joel Dragoo | TX | Northside Christian Academy | 2021 | 3B | 2024 | 7 | Phillies |
| Kohl Drake | TX | Wylie | 2018 | LHP | 2022 | 11 | Pirates |
| Isaiah Drake | GA | North Atlanta | 2023 | OF | 2023 | 5 | Braves |
| Dylan Dreiling | KS | Hays | 2022 | OF | 2024 | 2 | Rangers |
| Logan Driscoll | VA | Lake Braddock | 2016 | C | 2019 | Comp B | Padres |
| Tyler Driver | NC | Pro5 Academy | 2019 | RHP | 2019 | 18 | Seattle Mariners |
| Jay Driver | MA | Wellesley | 2020 | RHP | 2023 | 9 | Guardians |
| Shane Drohan | FL | Cardinal Newman | 2017 | LHP | 2017 | 23 | Phillies |
| Jake Drossner | PA | Council Rock North | 2012 | LHP | 2015 | 10 | Brewers |
| Hunter Dryden | GA | Veterans | 2022 | OF | 2024 | 17 | Giants |
| Conor Dryer | MO | Rockwood Summit | 2017 | OF | 2021 | 17 | Rays |
| Jayden Dubanewicz | FL | Stoneman Douglas | 2024 | RHP | 2024 | 16 | Brewers |
| Cody Dube | ME | Windham | 2012 | RHP | 2016 | 10 | Orioles |
| Kevin Duchene | IL | Joliet Catholic | 2012 | LHP | 2015 | 5 | Athletics |
| Cole Duensing | KS | Blue Valley Northwest | 2016 | RHP | 2016 | 6 | Angels |
| Brandon Dufault | NH | Windham | 2017 | RHP | 2021 | 16 | Los Angeles Angels |
| Mathew Duffy | ON | Assumption | 2020 | RHP | 2023 | 4 | Red Sox |
| Dayton Dugas | LA | Sam Houston | 2015 | OF | 2018 | 16 | Tigers |
| Gavin Dugas | LA | Houma Christian | 2018 | SS | 2023 | 6 | Nationals |
| Cameron Dulle | MO | Oakville | 2014 | - | 2019 | 30 | Cardinals |