Player Draft
| Name | State | School | Class | Pos. | Year | Round | Team |
| Titus Dumitru | OR | Sam Barlow | 2021 | 1B | 2024 | 16 | Braves |
| Andrew Duncan | FL | A3 Academy | 2023 | OF | 2023 | 19 | Astros |
| Andrew Dunford | GA | Houston County | 2023 | RHP | 2023 | 12 | Detroit Tigers |
| Clay Dungan | IN | Yorktown | 2015 | SS | 2019 | 9 | Royals |
| Elijah Dunham | IN | Evansville Reitz | 2017 | OF | 2019 | 40 | Pirates |
| Hayden Dunhurst | MS | Pearl River Central | 2019 | C | 2022 | 6 | Royals |
| Blake Dunn | MI | Saugatuck | 2017 | OF | 2021 | 15 | Cincinnati Reds |
| Nick Dunn | PA | Shikellamy | 2015 | 2B | 2018 | 5 | Cardinals |
| Ross Dunn | UT | Cottonwood | 2020 | LHP | 2023 | 10 | Twins |
| Parker Dunshee | IN | Zionsville | 2013 | RHP | 2017 | 7 | Athletics |
| Antoine Duplantis | LA | Lafayette | 2015 | OF | 2019 | 12th | Mets |
| Caleb Durbin | IL | Lake Forest | 2018 | SS | 2021 | 14 | Atlanta Braves |
| Brendan Durfee | CA | St Francis | 2020 | C | 2024 | 14 | Padres |
| Hayden Durke | LA | North Vermilion | 2020 | RHP | 2023 | 13 | Diamondbacks |
| Andrew Dutkanych IV | IN | Brebeuf | 2022 | RHP | 2024 | 7 | Cardinals |
| Dallas Dyar | MS | Clinton | 2019 | 3B | 2019 | 21 | Phillies |
| Connor Dykstra | BC | Sardis | 2019 | C | 2024 | NDFA | Seattle Mariners |
| Clark Eagan | WI | Appleton North | 2013 | OF | 2016 | 9 | Pirates |
| Daniel Eagen | NC | Fuquay-Varina | 2021 | RHP | 2024 | 3 | Diamondbacks |
| Jerrion Ealy | MS | Jackson Preparatory | 2019 | OF | 2019 | 31 | Diamondbacks |
| Connelly Early | VA | James River - Midlothian | 2020 | LHP | 2023 | 5 | Red Sox |
| Todd Eaton | IL | Greenville | 2010 | RHP | 2014 | 34 | Royals |
| Keenan Eaton | CO | Chaparral | 2014 | OF | 2014 | 39 | Phillies |
| Nathan Eaton | VA | Thomas Dale | 2015 | SS | 2018 | 21 | Royals |
| Konner Eaton | VA | Prince George | 2021 | LHP | 2024 | 6 | Rockies |
| Weston Eberly | FL | Bishop Moore | 2019 | - | 2023 | 16 | White Sox |
| Blake Ebo | NJ | Trenton Catholic | 2016 | OF | 2016 | 28 | Blue Jays |
| Steven Echavarria | NJ | Millburn | 2023 | RHP | 2023 | 3 | Athletics |
| Juan Javier Echevarria | FL | Osceola | 2015 | RHP | 2015 | 21 | Orioles |
| Matt Eckelman | KS | St. James | 2012 | RHP | 2016 | 21 | Pirates |
| Jake Eddington | MO | Doniphan | 2020 | RHP | 2023 | 7 | Phillies |
| Jake Eder | FL | Calvary Christian | 2017 | LHP | 2017 | 34 | Mets |
| Austin Edgette | PA | Downingtown East | 2013 | LHP | 2018 | 33 | Giants |
| Garrett Edwards | LA | Pitkin | 2020 | RHP | 2023 | 11 | Rays |
| Nick Egnatuk | NJ | Immaculata | 2017 | 3B | 2017 | 5 | Milwaukee Brewers |
| Zachary Ehrhard | FL | Wharton | 2021 | OF | 2024 | 4 | Red Sox |
| Austin Ehrlicher | CA | Santa Rosa | 2021 | RHP | 2022 | 18 | Boston |
| Johnny Eierman | MO | Warsaw | 2011 | SS | 2011 | 3 | Rays |
| Jeremy Eierman | MO | Warsaw | 2015 | SS | 2018 | CBB | Athletics |
| Brandon Eike | VA | Powhatan | 2020 | 3B | 2024 | 13 | Mariners |
| Josh Ekness | TX | The Woodlands | 2020 | RHP | 2023 | 12 | Marlins |
| Bryce Eldridge | VA | James Madison | 2023 | RHP | 2023 | 1 | Giants |
| Frank Elissalt | FL | Southwest Miami | 2020 | RHP | 2024 | 19 | Mets |
| Lucas Elissalt | FL | Southwest Miami Senior | 2022 | RHP | 2024 | 13 | Tigers |
| Jaron Elkins | TN | Goodpasture Christian | 2023 | OF | 2023 | 8 | Dodgers |
| Tim Elko | FL | Hillsborough | 2017 | 3B | 2022 | 10 | White Sox |
| Magnus Ellerts | VA | Woodbridge | 2019 | RHP | 2022 | 11 | Guardians |
| Hunter Elliot | MS | Tupelo | 2021 | LHP | 2024 | 20 | Dodgers |
| Clark Elliott | IL | Barrington | 2019 | OF | 2022 | CBB | Athletics |
| Evan Elliott | ON | Michael Power St. Joseph | 2019 | RHP | 2021 | 15 | Texas Rangers |
| Drew Ellis | IN | Jeffersonville | 2014 | SS | 2017 | 2 | DiamondBacks |
| James Ellwanger | TX | Magnolia West | 2023 | RHP | 2023 | 19 | Nationals |
| Austin Emener | GA | First Presbyterian Day | 2020 | LHP | 2023 | 16 | Colorado Rockies |
| Colt Emerson | OH | John Glenn | 2023 | SS | 2023 | 1 | Mariners |
| Cameron Enck | PA | Lampeter-Strasburg | 2015 | RHP | 2019 | 27 | Rockies |
| Scott Engler | KS | Bishop Carroll | 2015 | RHP | 2016 | 16 | Rangers |
| Blayne Enlow | LA | St Amant | 2017 | RHP | 2017 | 3 | Twins |
| Dietrich Enns | IL | Lincoln-Way East | 2009 | LHP | 2012 | 19 | Yankees |
| Kole Enright | FL | West Orange | 2016 | 3B | 2016 | 3 | Rangers |
| Nic Enright | VA | Steward | 2015 | RHP | 2019 | 20th | Indians |
| Dylan Eskew | FL | Sickles | 2019 | RHP | 2019 | 24th | Arizona Diamondbacks |
| Alan Espinal | FL | Viera | 2020 | C | 2024 | 11 | Rockies |
| Daniel Espino | GA | Georgia Premier Academy | 2019 | RHP | 2019 | 1st | Cleveland Indians |
| Tyler Esplin | FL | IMG Academy | 2017 | OF | 2017 | 7 | Red Sox |
| Gerardo Esquival | IL | De La Salle | 2009 | RHP | 2009 | 24 | Cubs |
| Chase Estep | KY | Corbin | 2019 | 3B | 2022 | 9 | Mets |
| Joey Estes | CA | Paraclete | 2019 | RHP | 2019 | 16 | Braves |
| Mack Estrada | FL | Northwest Florida State | 2023 | RHP | 2024 | 11 | Yankees |
| Ben Ethridge | MS | West Lauderdale | 2019 | RHP | 2022 | 15 | Twins |
| Matthew Etzel | TX | Clear Creek | 2020 | OF | 2023 | 10 | Orioles |
| Logan Evans | MI | Saline | 2019 | RHP | 2023 | 12 | Mariners |
| Ty Evans | FL | Lakeland Christian | 2021 | OF | 2021 | 20 | Atlanta Braves |
| Donye Evans | GA | Redan | 2020 | RHP | 2023 | 16 | Detroit Tigers |
| Zach Evans | NY | Lake Shore | 2020 | SS | 2024 | 9 | Padres |
| Kendal Ewell | IL | Marist | 2019 | OF | 2019 | 40 | Rockies |
| A.J. Ewing | OH | Springboro | 2023 | SS | 2023 | 4C | Mets |
| EJ Exposito | NY | St. John the Baptist | 2019 | SS | 2022 | 16 | Braves |
| Andrew Eyster | FL | Forest | 2017 | OF | 2017 | 27 | Diamondbacks |
| Judson Fabian | FL | Trinity Catholic | 2018 | OF | 2022 | CBB | Orioles |
| Jake Faherty | KY | Great Crossing | 2021 | RHP | 2024 | 11 | Mariners |
| Peter Fairbanks | MO | Webster Groves | 2012 | RHP | 2015 | 9 | Rangers |
| Justin Fall | NJ | Toms River South | 2017 | LHP | 2019 | 34 | Kansas City Royals |
| Sanson Faltine III | TX | Ft. Bend Travis | 2019 | SS | 2022 | 7 | Reds |
| Nick Fanti | NY | Hauppauge | 2015 | LHP | 2015 | 31 | Phillies |
| Jonny Farmelo | VA | Westfield | 2023 | OF | 2023 | 1 | Mariners |
| Greg Farone | NY | Schenectady | 2020 | LHP | 2024 | 7 | Giants |
| Logan Farrar | VA | Woodbridge | 2013 | OF | 2017 | 36 | Athletics |
| Mitch Farris | FL | Palm Harbor University | 2019 | OF | 2023 | 14 | Braves |
| Ethan Farris | TX | Cypress Woods | 2023 | 3B | 2023 | 18 | Tigers |
| Ian Farrow | FL | Merritt Island | 2020 | OF | 2024 | 14 | Pirates |
| Zachary Fascia | ON | Turner Fenton Secondary School | 2016 | C | 2021 | Free Agent | Cleveland Indians |
| Nate Fassnacht | PA | Ephrata | 2016 | SS | 2019 | 8 | Phillies |
| Caden Favors | OK | Carl Albert | 2020 | LHP | 2024 | 6 | Guardians |
| Wyatt Featherston | CO | Green Mountain | 2016 | OF | 2016 | 34 | Rockies |
| Kyler Fedko | PA | Vincentian Academy | 2018 | 2B | 2021 | 12 | Minnesota Twins |
| Hunter Feduccia | LA | Barbe | 2015 | C | 2018 | 12th | Dodgers |
| Cade Feeney | ND | Bismarck Century | 2020 | RHP | 2023 | 13 | Red Sox |
| Nick Feight | VA | Battlefield | 2013 | C | 2017 | 19 | Padres |
| Brady Feigl | MO | Parkway Central | 2014 | RHP | 2017 | 35 | Angels |
| Jose Felix | NY | Gregorio Luperon | 2020 | RHP | 2020 | Undrafted Free | Texas Rangers |