Player Draft
| Name | State | School | Class | Pos. | Year | Round | Team |
| Hunter Steinmetz | MO | Parkview | 2015 | OF | 2018 | 11 | Blue Jays |
| Jacob Steinmetz | NY | Hebrew Academy Five Towns and Rockaways | 2021 | RHP | 2021 | 3 | Arizona Diamondbacks |
| Anthony Stephan | NJ | Ridgewood | 2021 | SS | 2024 | 13 | Reds |
| Khal Stephen | IN | Seeger | 2021 | RHP | 2024 | 2 | Blue Jays |
| Seth Stephenson | TX | Jack C Hays | 2019 | OF | 2022 | 7 | Tigers |
| Levi Sterling | CA | Notre Dame | 2024 | RHP | 2024 | CB-A | Pirates |
| Zach Sterry | OH | Lexington | 2013 | OF | 2017 | 8 | Red Sox |
| Sammy Stevens | MI | Brother Rice | 2014 | C | 2014 | 34 | Tigers |
| Will Stevens | MO | Park Hill | 2019 | RHP | 2023 | 15 | Rays |
| Jake Stevenson | MN | Waconia | 2015 | RHP | 2019 | 10 | Reds |
| Tommy Stevenson | MO | Kirkwood | 2019 | C | 2022 | 19 | Athletics |
| Owen Stevenson | CA | Sacred Heart Cathedral | 2020 | RHP | 2023 | 19 | Rays |
| Brock Stewart | IL | Normal West | 2010 | RHP | 2014 | 6 | Dodgers |
| Joe Stewart | MI | Portage Central | 2016 | OF | 2022 | 9 | Angels |
| Devan (DJ) Stewart | MO | Westminster Christian | 2017 | SS | 2017 | 39 | Phillies |
| Carter Stewart | FL | Eau Gallie | 2018 | RHP | 2018 | 1st | Atlanta Braves |
| Sal Stewart | FL | Westminster Christian | 2022 | 3B | 2022 | 1C | Reds |
| Bradley Stewart | GA | West forsyth | 2026 | LHP | 2023 | 17 | Tigers |
| Bradley Stewart | FL | COOPER CITY HIGH SCHOOL | 2023 | LHP | 2023 | 17 | Tigers |
| Travis Sthele | TX | Ronald Reagan | 2020 | RHP | 2023 | 12 | Nationals |
| Jonathan Stiever | WI | Cedarburg | 2015 | RHP | 2018 | 5 | White Sox |
| Ian Stiffler | PA | Somerset Area | 2013 | RHP | 2013 | 7 | Braves |
| Matthew Stil | NJ | Cherokee | 2018 | RHP | 2019 | 21 | Kansas City Royals |
| Doug Still | MO | Sikeston | 2014 | LHP | 2017 | 11 | Giants |
| Tristan Stivors | TX | Medina Valley | 2017 | OF | 2022 | 16 | White Sox |
| Zach Stoner | IL | Rockford Boylan | 2012 | C | 2012 | 12 | White Sox |
| Justin Storm | MS | Madison Central | 2020 | LHP | 2023 | 7 | Marlins |
| Levi Stoudt | PA | Perkiomen School | 2016 | RHP | 2019 | 3 | Mariners |
| Eric Stout | IL | St. Francis | 2011 | LHP | 2014 | 13 | Royals |
| Peyton Stovall | LA | Haughton | 2021 | SS | 2024 | 4 | Reds |
| Brady Stover | IA | Collins- Maxwell-Baxter | 2016 | LHP | 2019 | 31 | Nationals |
| Josh Stowers | IL | Mount Carmel | 2015 | OF | 2018 | 2 | Mariners |
| Austin Strickland | OH | Moeller | 2020 | RHP | 2023 | 8 | Pirates |
| Samuel Strickland | AL | Briarwood Christian | 2017 | LHP | 2021 | 19 | Braves |
| Spencer Strider | TN | Christian Academy of Knoxville | 2017 | RHP | 2020 | 4th | Atlanta Braves |
| Jackson Strong | NY | West Seneca East | 2021 | OF | 2024 | 7 | Tigers |
| Tyler Stuart | IL | Herscher | 2018 | RHP | 2022 | 6 | Mets |
| Mason Studstill | FL | Rockledge | 2016 | RHP | 2016 | 22 | Indians |
| Sam Stuhr | OR | Madison | 2020 | RHP | 2024 | 5 | Athletics |
| Peyton Stumbo | CA | Placer | 2020 | SS | 2023 | 20 | Pirates |
| Cole Stupp | GA | Milton | 2019 | RHP | 2022 | 12 | Tigers |
| DeJohn Suber | IL | Morgan Park | 2012 | SS | 2012 | 38 | White Sox |
| Ryan Sublette | IL | Lemont | 2017 | RHP | 2021 | 7 | Los Angeles Dodgers |
| Zach Sullivan | NY | Corning Painted Post East | 2014 | OF | 2014 | 14 | Marlins |
| William Sullivan | FL | Dr. Phillips | 2019 | - | 2023 | 13 | Cardinals |
| Collin Sullivan | FL | Fort Pierce Central | 2016 | RHP | 2016 | 29 | Padres |
| Liam Sullivan | GA | Marist School | 2020 | LHP | 2023 | 13 | Washington Nationals |
| Sean Sullivan | CA | Chaminade College Prep | 2018 | RHP | 2021 | 8 | PIT |
| Sean Sullivan | MA | Tabor Academy | 2021 | LHP | 2023 | 2 | Rockies |
| Joseph Sullivan | AL | Vestavia Hills | 2021 | OF | 2024 | 7 | Astros |
| Cameron Sullivan | IN | Mt Vernon | 2024 | RHP | 2024 | 7 | Guardians |
| Brett Sunde | MI | Bishop Foley | 2012 | C | 2015 | 18 | Athletics |
| Jared Sundstrom | CA | Point Arena | 2019 | SS | 2023 | 10 | Mariners |
| Daniel Susac | CA | Jesuit | 2020 | C | 2022 | 1 | Athletics |
| Anthony Susac | CA | Jesuit | 2021 | RHP | 2024 | 8 | Rangers |
| Jack Suwinski | IL | Taft | 2016 | OF | 2016 | 15 | Padres |
| Matt Svanson | IL | Lake Zurich | 2017 | RHP | 2021 | 13 | Toronto Blue Jays |
| Travis Swaggerty | LA | Denham Springs | 2015 | OF | 2018 | 1st | Pirates |
| Eriq Swan | TN | Oakland | 2020 | RHP | 2023 | 4C | Dodgers |
| John Swanda | IA | Des Moines Roosevelt | 2017 | RHP | 2017 | 4 | Angels |
| Zach Swanson | WA | Toutle Lake | 2024 | RHP | 2024 | 9 | Tigers |
| Nate Sweeney | CO | Cherry Creek | 2016 | RHP | 2016 | 33 | Cubs |
| Jacob Sweeney | IN | Hobart | 2018 | LHP | 2019 | 36 | Pirates |
| Nicholas Swiney | NC | Hough | 2017 | LHP | 2020 | 2 | San Franciso Giants |
| Tyler Switalski | PA | Waynesburg Central | 2021 | LHP | 2024 | 16 | Giants |
| Andrew Sykes | IN | Valparaiso | 2014 | LHP | 2014 | 35 | Royals |
| Travis Sykora | TX | Round Rock | 2023 | RHP | 2023 | 3 | Nationals |
| Thomas Szapucki | FL | William T. Dwyer | 2015 | LHP | 2015 | 5 | Mets |
| Tommy Szczepanski | MI | Essexville Garber | 2022 | RHP | 2022 | 19 | Royals |
| Charlie Szykowny | IL | Alan B. Shepard | 2018 | SS | 2023 | 9 | Giats |
| Skylar Szynski | IN | Penn | 2016 | RHP | 2016 | 4 | Athletics |
| Matt Tabor | MA | Milton Academy | 2017 | RHP | 2017 | 3 | Diamondbacks |
| Zach Taglieri | FL | Port St Lucie | 2016 | RHP | 2016 | 40 | Dodgers |
| Logan Tanner | MS | George County | 2019 | C | 2022 | 2 | Reds |
| Deion Tansel | OH | Anthony Wayne | 2012 | SS | 2016 | 32 | Rays |
| Graysen Tarlow | CA | Orange Lutheran | 2020 | 3B | 2023 | 19 | Cardinals |
| Freddy Tarnok | FL | Riverview | 2017 | SS | 2017 | 3 | Braves |
| Derrick Tarpley Jr | PA | Brownsville Area | 2023 | OF | 2023 | 18 | Athletics |
| Andre Tarver | GA | Ringgold | 2019 | OF | 2019 | 15th | San Diego Padres |
| Mike Tauchman | IL | Fremd | 2009 | OF | 2013 | 10 | Rockies |
| Christian Taugner | IL | Lake Park | 2013 | RHP | 2017 | 37 | Brewers |
| Marshawn Taylor | IL | Simeon | 2013 | MIF | 2018 | 28 | Diamondbacks |
| Zac Taylor | IL | Downers Grove South | 2014 | OF | 2019 | 25 | Cubs |
| Owen Taylor | CO | Grand Junction | 2014 | 2B | 2014 | 27 | Blue Jays |
| Kobie Taylor | NH | Portsmouth | 2016 | OF | 2016 | 15 | Rangers |
| Evan Taylor | AL | Florence | 2018 | LHP | 2022 | 9 | Marlins |
| Andrew Taylor | MI | Caledonia | 2019 | RHP | 2022 | 2C | Astros |
| Grant Taylor | AL | Florence | 2021 | RHP | 2023 | 2 | White Sox |
| Troy Taylor | CA | Los Osos | 2019 | RHP | 2022 | 12 | Mariners |
| Brayden Taylor | UT | Copper Hills | 2020 | SS | 2023 | 1 | Rays |
| Will Taylor | SC | Dutch Fork | 2021 | OF | 2024 | 5 | Pirates |
| Nelson Taylor | FL | Clearwater | 2021 | OF | 2023 | 11 | Red Sox |
| Kavares Tears | TN | Columbia Academy | 2021 | OF | 2024 | 4C | Padres |
| Dylan TeBrake | MN | Rocori | 2018 | RHP | 2022 | 8 | Mets |
| Kyle Teel | NJ | Mahwah | 2020 | C | 2023 | 1 | Red Sox |
| Leury Tejada | NY | Walton Campus | 2018 | RHP | 2018 | 10th | Texas Rangers |
| Javier Santos Tejada | GA | Georgia Premier Academy | 2022 | RHP | 2022 | 7 | Guardians |
| Yoel Tejeda Jr | FL | North Broward Prep | 2022 | RHP | 2024 | 14 | Nationals |
| Mikey Tepper | SC | Fort Mill | 2020 | RHP | 2023 | 15 | Nationals |
| D'Marion Terrell | AL | Thompson | 2024 | OF | 2024 | 19 | Blue Jays |